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PhosphoLean – N-Oleoyl-PE & EGCG

PhosphoLean is a new ingredient being used in a number of non-prescription diet pills, such as LipidFX. PhosphoLean is a proprietary blend of a compound called N-Oleoyl-PE (a naturally-occurring phospholipid found in plants and animals) and EGCG (a catechin standardized from green tea extract).

PhosphoLean is a compound that contains green tea extract and a combination of phospholipids that may help to suppress appetite.

PhosphoLean is a compound that contains green tea extract and a combination of phospholipids that may help to suppress appetite.

Marketing for PhosphoLean states that it is “the advanced weight management tool”. The manufacturer, Cheminutra, claims that it uses the latest in state-of-the-art weight loss medication technologies through nutraceutical compounds for managing weight and keeping the appetite under control. Among the ingredients in this new diet pill ingredient is a combination of natural substances believed to impact the sensation of hunger so that it can potentially assist in limiting the amount of food a dieter consumes. Thus, PhosphoLean is promoted as an appetite suppressant.

N-Oleoyl-PE is the compound in PhosphoLean that is believed to be responsible for directly suppressing appetite. When ingested and present in the digestive tract, a compound in N-Oleoyl-PE binds to a cell receptor called activated receptor-alpha (PPAR-). When these receptors are activated by this binding action, they send a signal to the brain that decreases appetite.

The PhosphoLean formula also contains epigallocatechin gallate (EGCG), which is a catechin that can be found in foods such as green tea. Essentially, EGCG is a flavonoid that it is believed can behave as a highly effective antioxidant, which is helpful for reducing the damage made by free radicals to the cells of the body. It is believed that antioxidants such as EGCG can also increase the rate of fat oxidation in the body, thus increasing body fat utilization for energy (fat burning). In the medical industry, though, antioxidants such as EGCG are recognized much more for their benefits in preventing cancer than any impact on weight loss.

The foundation of the claims for the effectiveness of PhosphoLean as an effective weight loss aid is based on two functions: the suppression of appetite and increased thermogenesis (fat burning). These functions become effective, according to the marketing materials, when they are combined with “healthy lifestyle choices”.

Though there may be some appetite suppression as a result of taking the weight loss supplement PhosphoLean, and there may also be cellular protection benefits due to the antioxidants it contains, at the time of this review there is yet to be much evidence to substantiate these claims. Currently, the only clinical studies that have been conducted with PhosphoLean were based on trials with rats, not people. That being said, PhosphoLean is a relatively new weight loss product and only time will tell if this compound is truly effective in humans.

It is appreciated that the marketing materials for PhosphoLean do highly encourage a healthy nutritious diet and regular exercise in order to see the best results when using this clinically tested product. Keep in mind, though, that while hunger may be reduced in some users, there is no ingredient in the formula that is proven to actively burn fat.

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